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Anticancer and Anti-Inflammatory Activities of Some New Pyrazolo[3,4-b]pyrazines

New derivatives of pyrazolo[3,4-b]pyrazines and related heterocycles were synthesized using 5-amino-3-methyl-4-nitroso-1-phenyl-pyrazole (1) as a starting material. The 5-acetyl derivative 15 was shown to be a useful key intermediate for the synthesis of several derivatives of pyrazolopyrazines. Som...

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Detalles Bibliográficos
Autores principales:	El-Kashef, Hussein, El-Emary, Talaat, Verhaeghe, Pierre, Vanelle, Patrice, Samy, Maha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222508/ https://www.ncbi.nlm.nih.gov/pubmed/30332801 http://dx.doi.org/10.3390/molecules23102657

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