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Synthesis and Cytoprotective Characterization of 8-Hydroxyquinoline Betti Products

The 8-hydroxyquinoline pharmacophore scaffold has been shown to possess a range of activities as metal chelation, enzyme inhibition, cytotoxicity, and cytoprotection. Based on our previous findings we set out to optimize the scaffold for cytoprotective activity for its potential application in centr...

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Detalles Bibliográficos
Autores principales: Kanizsai, Iván, Madácsi, Ramóna, Hackler Jr., László, Gyuris, Márió, Szebeni, Gábor J., Huzián, Orsolya, Puskás, László G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222637/
https://www.ncbi.nlm.nih.gov/pubmed/30072653
http://dx.doi.org/10.3390/molecules23081934

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