Cargando…

Synthesis of New 1,3,5-Triazine-Based 2-Pyrazolines as Potential Anticancer Agents

A new series of 1,3,5-triazine-containing 2-pyrazoline derivatives (8–11)a–g was synthesized by cyclocondensation reactions of [(4,6-bis((2-hydroxyethyl)amino)-1,3,5-triazin-2-yl)amine]chalcones 7a–g with hydrazine hydrate and derivatives. Chalcones 7a–g were obtained by Claisen-Schmidt condensation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moreno, Leydi M., Quiroga, Jairo, Abonia, Rodrigo, Ramírez-Prada, Jonathan, Insuasty, Braulio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222643/ https://www.ncbi.nlm.nih.gov/pubmed/30082588 http://dx.doi.org/10.3390/molecules23081956

Ejemplares similares

Synthesis, biological evaluation, and in silico studies of novel chalcone- and pyrazoline-based 1,3,5-triazines as potential anticancer agents
por: Moreno, Leydi M., et al.
Publicado: (2020)

Synthesis and in Vitro Antitumor Activity of a Novel Series of 2-Pyrazoline Derivatives Bearing the 4-Aryloxy-7-chloroquinoline Fragment
por: Montoya, Alba, et al.
Publicado: (2014)

Hybrid Molecules Containing a 7-Chloro-4-aminoquinoline Nucleus and a Substituted 2-Pyrazoline with Antiproliferative and Antifungal Activity
por: Montoya, Alba, et al.
Publicado: (2016)

Synthesis and DFT Calculations of Novel Vanillin-Chalcones and Their 3-Aryl-5-(4-(2-(dimethylamino)-ethoxy)-3-methoxyphenyl)-4,5-dihydro-1H-pyrazole-1-carbaldehyde Derivatives as Antifungal Agents
por: Illicachi, Luis Alberto, et al.
Publicado: (2017)

Design of Two Alternative Routes for the Synthesis of Naftifine and Analogues as Potential Antifungal Agents
por: Abonia, Rodrigo, et al.
Publicado: (2018)

Microwave-Assisted Synthesis of Novel Pyrazolo[3,4-g][1,8]naphthyridin-5-amine with Potential Antifungal and Antitumor Activity
por: Acosta, Paola, et al.
Publicado: (2015)

Synthesis, Anticancer and Antitubercular Properties of New Chalcones and Their Nitrogen-Containing Five-Membered Heterocyclic Hybrids Bearing Sulfonamide Moiety
por: Castaño, Lina Fernanda, et al.
Publicado: (2022)

Anticancer activity of pyrimidodiazepines based on 2-chloro-4-anilinoquinazoline: synthesis, DNA binding and molecular docking
por: Cuartas, Viviana, et al.
Publicado: (2021)

Synthesis, Antifungal and Antitumor Activity of Novel (Z)-5-Hetarylmethylidene-1,3-thiazol-4-ones and (Z)-5-Ethylidene-1,3-thiazol-4-ones
por: Insuasty, Alberto, et al.
Publicado: (2013)

Highly Efficient and Diastereoselective Synthesis of New Pyrazolylpyrrolizine and Pyrazolylpyrrolidine Derivates by a Three-Component Domino Process
por: Quiroga, Jairo, et al.
Publicado: (2014)

Synthesis of 1-Benzyl-6-(4-chlorophenyl)-2-(4-R-phenyl)-4-(4-R-styryl)-2,3-dihydropyrazolo[3,4-b][1,4]diazepines‡
por: Insuasty, Braulio, et al.
Publicado: (2001)

Biguanide-Based Synthesis of 1,3,5-Triazine Derivatives with Anticancer Activity and 1,3,5-Triazine Incorporated Calcium Citrate Nanoparticles
por: Chalermnon, Monnaya, et al.
Publicado: (2021)

Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents
por: Karabacak, Muhammed, et al.
Publicado: (2015)

Synthesis, Characterization and Fluorescent Property Evaluation of 1,3,5-Triaryl-2-pyrazolines
por: Hasan, Aurangzeb, et al.
Publicado: (2011)

Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines
por: Gul, Halise Inci, et al.
Publicado: (2016)

Antimicrobial Activity of Quinoline-Based Hydroxyimidazolium Hybrids
por: Insuasty, Daniel, et al.
Publicado: (2019)

Catalyst-free assembly of giant tris(heteroaryl)methanes: synthesis of novel pharmacophoric triads and model sterically crowded tris(heteroaryl/aryl)methyl cation salts
por: Abonia, Rodrigo, et al.
Publicado: (2019)

Pyrazoline Hybrids as Promising Anticancer Agents: An Up-to-Date Overview
por: Matiadis, Dimitris, et al.
Publicado: (2020)

QSAR Studies, Molecular Docking, Molecular Dynamics, Synthesis, and Biological Evaluation of Novel Quinolinone-Based Thiosemicarbazones against Mycobacterium tuberculosis
por: Valencia, Jhesua, et al.
Publicado: (2022)

Synthesis of Novel Benzodifuranyl; 1,3,5-Triazines; 1,3,5-Oxadiazepines; and Thiazolopyrimidines Derived from Visnaginone and Khellinone as Anti-Inflammatory and Analgesic Agents
por: Abu-Hashem, Ameen Ali, et al.
Publicado: (2020)

Triazine: An Important Building Block of Organic Materials for Solar Cell Application
por: Dávila Cerón, Valeria, et al.
Publicado: (2022)

The longstanding challenge of the nanocrystallization of 1,3,5-trinitroperhydro-1,3,5-triazine (RDX)
por: Pessina, Florent, et al.
Publicado: (2017)

An improved synthesis of 1,3,5-triaryl-2-pyrazolines in acetic acid aqueous solution under ultrasound irradiation
por: Li, Ji-Tai, et al.
Publicado: (2007)

Synthesis and Evaluation of New Pyrazoline Derivatives as Potential Anticancer Agents in HepG-2 Cell Line
por: Xu, Weijie, et al.
Publicado: (2017)

Design and efficient synthesis of pyrazoline and isoxazole bridged indole C-glycoside hybrids as potential anticancer agents
por: Kumari, Priti, et al.
Publicado: (2020)

In Silico and in Vitro-Guided Identification of Inhibitors of Alkylquinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa
por: Soukarieh, Fadi, et al.
Publicado: (2018)

Synthesis and photo-physical properties of fluorescent 1,3,5-triazine styryl derivatives
por: Padalkar, Vikas S, et al.
Publicado: (2011)

Design and Synthesis of New 1,3,5‐Trisubstituted Triazines for the Treatment of Cancer and Inflammation
por: Zacharie, Boulos, et al.
Publicado: (2018)

Recent Advances in the Synthesis of Propargyl Derivatives, and Their Application as Synthetic Intermediates and Building Blocks †
por: Abonia, Rodrigo, et al.
Publicado: (2023)

Catalyst-free synthesis of tetrahydropyrimidines via formal [3+3]-cycloaddition of imines with 1,3,5-hexahydro-1,3,5-triazines
por: Chen, Long, et al.
Publicado: (2018)

Synthesis, characterization and evaluation of 1,3,5-triazine aminobenzoic acid derivatives for their antimicrobial activity
por: Al-Zaydi, Khadijah M., et al.
Publicado: (2017)

Multicomponent Molecular Systems Based on Porphyrins, 1,3,5-Triazine and Carboranes: Synthesis and Characterization
por: Alpatova, Victoria M., et al.
Publicado: (2022)

Microwave-Assisted Sequential One-Pot Synthesis of 8-Substituted Pyrazolo[1,5-a][1,3,5]triazines
por: Elie, Jonathan, et al.
Publicado: (2021)

Novel 3,4-Methylenedioxybenzene Scaffold Incorporated 1,3,5-Trisubstituted-2-pyrazolines: Synthesis, Characterization and Evaluation for Chemotherapeutic Activity
por: Deshpande, S. R., et al.
Publicado: (2015)

Selective Synthesis of N-[1,3,5]Triazinyl-α-Ketoamides and N-[1,3,5]Triazinyl-Amides from the Reactions of 2-Amine-[1,3,5]Triazines with Ketones
por: Li, Yue, et al.
Publicado: (2023)

Substituted 1,3,5-Triazine Hexacarboxylates as Potential Linkers for MOFs
por: Klinkebiel, Arne, et al.
Publicado: (2019)

Publisher Correction: Design and efficient synthesis of pyrazoline and isoxazole bridged indole C-glycoside hybrids as potential anticancer agents
por: Kumari, Priti, et al.
Publicado: (2020)

Synthesis, Characterization and Biological Evaluation of Magnolol and Honokiol Derivatives with 1,3,5-Triazine of Metformin Cyclization
por: Ren, Cui, et al.
Publicado: (2020)

Pyrazoles and Pyrazolines as Anti-Inflammatory Agents
por: Mantzanidou, Martha, et al.
Publicado: (2021)

Novel Sulfonamide–Triazine Hybrid Derivatives: Docking, Synthesis, and Biological Evaluation as Anticancer Agents
por: Alelaimat, Mahmoud A., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mkad112cgie4e1smerhg7cb8hi