Transition-Metal-Free C(sp(3))–H Oxidation of Diarylmethanes

An efficient direct C(sp3)–H oxidation of diarylmethanes has been demonstrated by this study. This method employs environment-friendly O(2) as an oxidant and is promoted by commercially available MN(SiMe(3))(2) [M = K, Na or Li], which provides a facile method for the synthesis of various diaryl ket...

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Autores principales: Yang, Fan, Zhou, Bihui, Chen, Pu, Zou, Dong, Luo, Qiannan, Ren, Wenzhe, Li, Linlin, Fan, Limei, Li, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222647/
https://www.ncbi.nlm.nih.gov/pubmed/30071657
http://dx.doi.org/10.3390/molecules23081922
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author Yang, Fan
Zhou, Bihui
Chen, Pu
Zou, Dong
Luo, Qiannan
Ren, Wenzhe
Li, Linlin
Fan, Limei
Li, Jie
author_facet Yang, Fan
Zhou, Bihui
Chen, Pu
Zou, Dong
Luo, Qiannan
Ren, Wenzhe
Li, Linlin
Fan, Limei
Li, Jie
author_sort Yang, Fan
collection PubMed
description An efficient direct C(sp3)–H oxidation of diarylmethanes has been demonstrated by this study. This method employs environment-friendly O(2) as an oxidant and is promoted by commercially available MN(SiMe(3))(2) [M = K, Na or Li], which provides a facile method for the synthesis of various diaryl ketones in excellent yields. This protocol is metal-free, mild and compatible with a number of functional groups on substrates.
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spelling pubmed-62226472018-11-13 Transition-Metal-Free C(sp(3))–H Oxidation of Diarylmethanes Yang, Fan Zhou, Bihui Chen, Pu Zou, Dong Luo, Qiannan Ren, Wenzhe Li, Linlin Fan, Limei Li, Jie Molecules Communication An efficient direct C(sp3)–H oxidation of diarylmethanes has been demonstrated by this study. This method employs environment-friendly O(2) as an oxidant and is promoted by commercially available MN(SiMe(3))(2) [M = K, Na or Li], which provides a facile method for the synthesis of various diaryl ketones in excellent yields. This protocol is metal-free, mild and compatible with a number of functional groups on substrates. MDPI 2018-08-01 /pmc/articles/PMC6222647/ /pubmed/30071657 http://dx.doi.org/10.3390/molecules23081922 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Yang, Fan
Zhou, Bihui
Chen, Pu
Zou, Dong
Luo, Qiannan
Ren, Wenzhe
Li, Linlin
Fan, Limei
Li, Jie
Transition-Metal-Free C(sp(3))–H Oxidation of Diarylmethanes
title Transition-Metal-Free C(sp(3))–H Oxidation of Diarylmethanes
title_full Transition-Metal-Free C(sp(3))–H Oxidation of Diarylmethanes
title_fullStr Transition-Metal-Free C(sp(3))–H Oxidation of Diarylmethanes
title_full_unstemmed Transition-Metal-Free C(sp(3))–H Oxidation of Diarylmethanes
title_short Transition-Metal-Free C(sp(3))–H Oxidation of Diarylmethanes
title_sort transition-metal-free c(sp(3))–h oxidation of diarylmethanes
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222647/
https://www.ncbi.nlm.nih.gov/pubmed/30071657
http://dx.doi.org/10.3390/molecules23081922
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