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Attempted Synthesis of Vinca Alkaloids Condensed with Three-Membered Rings

Our successful work for the synthesis of cyclopropanated vinblastine and its derivatives by the Simmons–Smith reaction was followed to build up further three-membered rings into the 14,15-position of the vindoline part of the dimer alkaloid. Halogenated 14,15-cyclopropanovindoline was prepared by re...

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Detalles Bibliográficos
Autores principales: Keglevich, András, Mayer, Szabolcs, Pápai, Réka, Szigetvári, Áron, Sánta, Zsuzsanna, Dékány, Miklós, Szántay, Csaba, Keglevich, Péter, Hazai, László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222653/
https://www.ncbi.nlm.nih.gov/pubmed/30304796
http://dx.doi.org/10.3390/molecules23102574

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