Synthesis of Novel 1,4-Naphthoquinones Possessing Indole Scaffolds Using In(OTf)(3) in Solvent-Free Conditions

Novel 1,4-naphthoquinones possessing indole scaffolds were prepared by the reaction of 2-hydroxy-1,4-naphthoquinone-substituted salicylic aldehydes and indoles using In(OTf)(3) as a catalyst. The method has the advantages of simple operation, mild reaction conditions, and friendly environment.

Detalles Bibliográficos
Autores principales: Yang, Xiaojuan, Wu, Liqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222671/
https://www.ncbi.nlm.nih.gov/pubmed/30082583
http://dx.doi.org/10.3390/molecules23081954
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author Yang, Xiaojuan
Wu, Liqiang
author_facet Yang, Xiaojuan
Wu, Liqiang
author_sort Yang, Xiaojuan
collection PubMed
description Novel 1,4-naphthoquinones possessing indole scaffolds were prepared by the reaction of 2-hydroxy-1,4-naphthoquinone-substituted salicylic aldehydes and indoles using In(OTf)(3) as a catalyst. The method has the advantages of simple operation, mild reaction conditions, and friendly environment.
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spelling pubmed-62226712018-11-13 Synthesis of Novel 1,4-Naphthoquinones Possessing Indole Scaffolds Using In(OTf)(3) in Solvent-Free Conditions Yang, Xiaojuan Wu, Liqiang Molecules Article Novel 1,4-naphthoquinones possessing indole scaffolds were prepared by the reaction of 2-hydroxy-1,4-naphthoquinone-substituted salicylic aldehydes and indoles using In(OTf)(3) as a catalyst. The method has the advantages of simple operation, mild reaction conditions, and friendly environment. MDPI 2018-08-06 /pmc/articles/PMC6222671/ /pubmed/30082583 http://dx.doi.org/10.3390/molecules23081954 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yang, Xiaojuan
Wu, Liqiang
Synthesis of Novel 1,4-Naphthoquinones Possessing Indole Scaffolds Using In(OTf)(3) in Solvent-Free Conditions
title Synthesis of Novel 1,4-Naphthoquinones Possessing Indole Scaffolds Using In(OTf)(3) in Solvent-Free Conditions
title_full Synthesis of Novel 1,4-Naphthoquinones Possessing Indole Scaffolds Using In(OTf)(3) in Solvent-Free Conditions
title_fullStr Synthesis of Novel 1,4-Naphthoquinones Possessing Indole Scaffolds Using In(OTf)(3) in Solvent-Free Conditions
title_full_unstemmed Synthesis of Novel 1,4-Naphthoquinones Possessing Indole Scaffolds Using In(OTf)(3) in Solvent-Free Conditions
title_short Synthesis of Novel 1,4-Naphthoquinones Possessing Indole Scaffolds Using In(OTf)(3) in Solvent-Free Conditions
title_sort synthesis of novel 1,4-naphthoquinones possessing indole scaffolds using in(otf)(3) in solvent-free conditions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222671/
https://www.ncbi.nlm.nih.gov/pubmed/30082583
http://dx.doi.org/10.3390/molecules23081954
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AT wuliqiang synthesisofnovel14naphthoquinonespossessingindolescaffoldsusinginotf3insolventfreeconditions

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