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Evaluation of the Antioxidant and Neuroprotectant Activities of New Asymmetrical 1,3-Diketones

A series of fourteen new asymmetrical 1,3-diketone derivatives have been synthesized and evaluated in the ABTS, FRAP and DPPH assays as a new chemotype with antioxidant and drug-like properties. All the compounds displayed low cytotoxicity in comparison to curcumin against the human neuroblastoma SH...

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Detalles Bibliográficos
Autores principales: Nieto, Carla I., Cornago, María Pilar, Cabildo, María Pilar, Sanz, Dionisia, Claramunt, Rosa M., Torralba, María Carmen, Torres, María Rosario, Martínez Casanova, Diana, Sánchez-Alegre, Yaiza Rebeca, Escudero, Esther, Lavandera, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222706/
https://www.ncbi.nlm.nih.gov/pubmed/30042315
http://dx.doi.org/10.3390/molecules23081837

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