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Acetylene in Organic Synthesis: Recent Progress and New Uses
Recent progress in the leading synthetic applications of acetylene is discussed from the prospect of rapid development and novel opportunities. A diversity of reactions involving the acetylene molecule to carry out vinylation processes, cross-coupling reactions, synthesis of substituted alkynes, pre...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222752/ https://www.ncbi.nlm.nih.gov/pubmed/30250005 http://dx.doi.org/10.3390/molecules23102442 |
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author | Voronin, Vladimir V. Ledovskaya, Maria S. Bogachenkov, Alexander S. Rodygin, Konstantin S. Ananikov, Valentine P. |
author_facet | Voronin, Vladimir V. Ledovskaya, Maria S. Bogachenkov, Alexander S. Rodygin, Konstantin S. Ananikov, Valentine P. |
author_sort | Voronin, Vladimir V. |
collection | PubMed |
description | Recent progress in the leading synthetic applications of acetylene is discussed from the prospect of rapid development and novel opportunities. A diversity of reactions involving the acetylene molecule to carry out vinylation processes, cross-coupling reactions, synthesis of substituted alkynes, preparation of heterocycles and the construction of a number of functionalized molecules with different levels of molecular complexity were recently studied. Of particular importance is the utilization of acetylene in the synthesis of pharmaceutical substances and drugs. The increasing interest in acetylene and its involvement in organic transformations highlights a fascinating renaissance of this simplest alkyne molecule. |
format | Online Article Text |
id | pubmed-6222752 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62227522018-11-13 Acetylene in Organic Synthesis: Recent Progress and New Uses Voronin, Vladimir V. Ledovskaya, Maria S. Bogachenkov, Alexander S. Rodygin, Konstantin S. Ananikov, Valentine P. Molecules Review Recent progress in the leading synthetic applications of acetylene is discussed from the prospect of rapid development and novel opportunities. A diversity of reactions involving the acetylene molecule to carry out vinylation processes, cross-coupling reactions, synthesis of substituted alkynes, preparation of heterocycles and the construction of a number of functionalized molecules with different levels of molecular complexity were recently studied. Of particular importance is the utilization of acetylene in the synthesis of pharmaceutical substances and drugs. The increasing interest in acetylene and its involvement in organic transformations highlights a fascinating renaissance of this simplest alkyne molecule. MDPI 2018-09-24 /pmc/articles/PMC6222752/ /pubmed/30250005 http://dx.doi.org/10.3390/molecules23102442 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Voronin, Vladimir V. Ledovskaya, Maria S. Bogachenkov, Alexander S. Rodygin, Konstantin S. Ananikov, Valentine P. Acetylene in Organic Synthesis: Recent Progress and New Uses |
title | Acetylene in Organic Synthesis: Recent Progress and New Uses |
title_full | Acetylene in Organic Synthesis: Recent Progress and New Uses |
title_fullStr | Acetylene in Organic Synthesis: Recent Progress and New Uses |
title_full_unstemmed | Acetylene in Organic Synthesis: Recent Progress and New Uses |
title_short | Acetylene in Organic Synthesis: Recent Progress and New Uses |
title_sort | acetylene in organic synthesis: recent progress and new uses |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222752/ https://www.ncbi.nlm.nih.gov/pubmed/30250005 http://dx.doi.org/10.3390/molecules23102442 |
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