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Acetylene in Organic Synthesis: Recent Progress and New Uses

Recent progress in the leading synthetic applications of acetylene is discussed from the prospect of rapid development and novel opportunities. A diversity of reactions involving the acetylene molecule to carry out vinylation processes, cross-coupling reactions, synthesis of substituted alkynes, pre...

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Autores principales: Voronin, Vladimir V., Ledovskaya, Maria S., Bogachenkov, Alexander S., Rodygin, Konstantin S., Ananikov, Valentine P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222752/
https://www.ncbi.nlm.nih.gov/pubmed/30250005
http://dx.doi.org/10.3390/molecules23102442
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author Voronin, Vladimir V.
Ledovskaya, Maria S.
Bogachenkov, Alexander S.
Rodygin, Konstantin S.
Ananikov, Valentine P.
author_facet Voronin, Vladimir V.
Ledovskaya, Maria S.
Bogachenkov, Alexander S.
Rodygin, Konstantin S.
Ananikov, Valentine P.
author_sort Voronin, Vladimir V.
collection PubMed
description Recent progress in the leading synthetic applications of acetylene is discussed from the prospect of rapid development and novel opportunities. A diversity of reactions involving the acetylene molecule to carry out vinylation processes, cross-coupling reactions, synthesis of substituted alkynes, preparation of heterocycles and the construction of a number of functionalized molecules with different levels of molecular complexity were recently studied. Of particular importance is the utilization of acetylene in the synthesis of pharmaceutical substances and drugs. The increasing interest in acetylene and its involvement in organic transformations highlights a fascinating renaissance of this simplest alkyne molecule.
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spelling pubmed-62227522018-11-13 Acetylene in Organic Synthesis: Recent Progress and New Uses Voronin, Vladimir V. Ledovskaya, Maria S. Bogachenkov, Alexander S. Rodygin, Konstantin S. Ananikov, Valentine P. Molecules Review Recent progress in the leading synthetic applications of acetylene is discussed from the prospect of rapid development and novel opportunities. A diversity of reactions involving the acetylene molecule to carry out vinylation processes, cross-coupling reactions, synthesis of substituted alkynes, preparation of heterocycles and the construction of a number of functionalized molecules with different levels of molecular complexity were recently studied. Of particular importance is the utilization of acetylene in the synthesis of pharmaceutical substances and drugs. The increasing interest in acetylene and its involvement in organic transformations highlights a fascinating renaissance of this simplest alkyne molecule. MDPI 2018-09-24 /pmc/articles/PMC6222752/ /pubmed/30250005 http://dx.doi.org/10.3390/molecules23102442 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Voronin, Vladimir V.
Ledovskaya, Maria S.
Bogachenkov, Alexander S.
Rodygin, Konstantin S.
Ananikov, Valentine P.
Acetylene in Organic Synthesis: Recent Progress and New Uses
title Acetylene in Organic Synthesis: Recent Progress and New Uses
title_full Acetylene in Organic Synthesis: Recent Progress and New Uses
title_fullStr Acetylene in Organic Synthesis: Recent Progress and New Uses
title_full_unstemmed Acetylene in Organic Synthesis: Recent Progress and New Uses
title_short Acetylene in Organic Synthesis: Recent Progress and New Uses
title_sort acetylene in organic synthesis: recent progress and new uses
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222752/
https://www.ncbi.nlm.nih.gov/pubmed/30250005
http://dx.doi.org/10.3390/molecules23102442
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