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Failure of the Anti-Inflammatory Parasitic Worm Product ES-62 to Provide Protection in Mouse Models of Type I Diabetes, Multiple Sclerosis, and Inflammatory Bowel Disease

Parasitic helminths and their isolated secreted products show promise as novel treatments for allergic and autoimmune conditions in humans. Foremost amongst the secreted products is ES-62, a glycoprotein derived from Acanthocheilonema viteae, a filarial nematode parasite of gerbils, which is anti-in...

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Detalles Bibliográficos
Autores principales: Doonan, James, Thomas, David, Wong, Michelle H., Ramage, Hazel J., Al-Riyami, Lamyaa, Lumb, Felicity E., Bell, Kara S., Fairlie-Clarke, Karen J., Suckling, Colin J., Michelsen, Kathrin S., Jiang, Hui-Rong, Cooke, Anne, Harnett, Margaret M., Harnett, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222842/
https://www.ncbi.nlm.nih.gov/pubmed/30336585
http://dx.doi.org/10.3390/molecules23102669