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Failure of the Anti-Inflammatory Parasitic Worm Product ES-62 to Provide Protection in Mouse Models of Type I Diabetes, Multiple Sclerosis, and Inflammatory Bowel Disease
Parasitic helminths and their isolated secreted products show promise as novel treatments for allergic and autoimmune conditions in humans. Foremost amongst the secreted products is ES-62, a glycoprotein derived from Acanthocheilonema viteae, a filarial nematode parasite of gerbils, which is anti-in...
Autores principales: | Doonan, James, Thomas, David, Wong, Michelle H., Ramage, Hazel J., Al-Riyami, Lamyaa, Lumb, Felicity E., Bell, Kara S., Fairlie-Clarke, Karen J., Suckling, Colin J., Michelsen, Kathrin S., Jiang, Hui-Rong, Cooke, Anne, Harnett, Margaret M., Harnett, William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222842/ https://www.ncbi.nlm.nih.gov/pubmed/30336585 http://dx.doi.org/10.3390/molecules23102669 |
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