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Machine Learning Approaches for Protein–Protein Interaction Hot Spot Prediction: Progress and Comparative Assessment

Hot spots are the subset of interface residues that account for most of the binding free energy, and they play essential roles in the stability of protein binding. Effectively identifying which specific interface residues of protein–protein complexes form the hot spots is critical for understanding...

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Detalles Bibliográficos
Autores principales: Liu, Siyu, Liu, Chuyao, Deng, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222875/
https://www.ncbi.nlm.nih.gov/pubmed/30287797
http://dx.doi.org/10.3390/molecules23102535

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