Development of an In Vitro Screening Platform for the Identification of Partial PPARγ Agonists as a Source for Antidiabetic Lead Compounds

Type 2 diabetes (T2D) is a metabolic disorder where insulin-sensitive tissues show reduced sensitivity towards insulin and a decreased glucose uptake (GU), which leads to hyperglycaemia. Peroxisome proliferator-activated receptor (PPAR)γ plays an important role in lipid and glucose homeostasis and i...

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Detalles Bibliográficos
Autores principales: Porskjær Christensen, Lars, Bahij El-Houri, Rime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222920/
https://www.ncbi.nlm.nih.gov/pubmed/30248999
http://dx.doi.org/10.3390/molecules23102431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222920/
https://www.ncbi.nlm.nih.gov/pubmed/30248999
http://dx.doi.org/10.3390/molecules23102431

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