Disruption of VEGF Mediated Flk‐1 Signaling Leads to a Gradual Loss of Vessel Health and Cardiac Function During Myocardial Infarction: Potential Therapy With Pellino‐1

BACKGROUND: The present study demonstrates that the ubiquitin E3 ligase, Pellino‐1 (Peli1), is an important angiogenic molecule under the control of vascular endothelial growth factor (VEGF) receptor 2/Flk‐1. We have previously reported increased survivability of ischemic skin flap tissue by adenovi...

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Detalles Bibliográficos
Autores principales: Thirunavukkarasu, Mahesh, Selvaraju, Vaithinathan, Joshi, Mandip, Coca‐Soliz, Vladimir, Tapias, Leonidas, Saad, IbnalWalid, Fournier, Craig, Husain, Aaftab, Campbell, Jacob, Yee, Siu‐Pok, Sanchez, Juan A., Palesty, J. Alexander, McFadden, David W., Maulik, Nilanjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222946/
https://www.ncbi.nlm.nih.gov/pubmed/30371196
http://dx.doi.org/10.1161/JAHA.117.007601

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