SRC inhibition prevents P-cadherin mediated signaling and function in basal-like breast cancer cells

BACKGROUND: Basal-like breast cancer (BLBC) is a poor prognosis subgroup of triple-negative carcinomas that still lack specific target therapies and accurate biomarkers for treatment selection. P-cadherin is frequently overexpressed in these tumors, promoting cell invasion, stem cell activity and tu...

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Detalles Bibliográficos
Autores principales: Ribeiro, Ana Sofia, Nobre, Ana Rita, Mendes, Nuno, Almeida, João, Vieira, André Filipe, Sousa, Bárbara, Carvalho, Filomena A., Monteiro, Joana, Polónia, António, Fonseca, Martina, Sanches, João Miguel, Santos, Nuno C., Seruca, Raquel, Paredes, Joana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223051/
https://www.ncbi.nlm.nih.gov/pubmed/30404626
http://dx.doi.org/10.1186/s12964-018-0286-2

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