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A review of antibiotic prophylaxis for traveler’s diarrhea: past to present

As there is rapid increase in international travel to tropical and subtropical countries, there will likely be more people exposed to diarrheal pathogens in these moderate to high risk areas and subsequent increased concern for traveler’s diarrhea. The disease may appear as a mild clinical syndrome,...

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Autores principales: Diptyanusa, Ajib, Ngamprasertchai, Thundon, Piyaphanee, Watcharapong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223076/
https://www.ncbi.nlm.nih.gov/pubmed/30455974
http://dx.doi.org/10.1186/s40794-018-0074-4
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author Diptyanusa, Ajib
Ngamprasertchai, Thundon
Piyaphanee, Watcharapong
author_facet Diptyanusa, Ajib
Ngamprasertchai, Thundon
Piyaphanee, Watcharapong
author_sort Diptyanusa, Ajib
collection PubMed
description As there is rapid increase in international travel to tropical and subtropical countries, there will likely be more people exposed to diarrheal pathogens in these moderate to high risk areas and subsequent increased concern for traveler’s diarrhea. The disease may appear as a mild clinical syndrome, yet a more debilitating presentation can lead to itinerary changes and hospitalization. As bacterial etiologies are the most common causative agents of TD, the use of antibiotic prophylaxis to prevent TD has been reported among travelers for several years. The most common type of antibiotic used for TD has changed over 50 years, depending on many influencing factors. The use of antibiotic prophylaxis for TD prevention in travelers is still controversial, mainly because of difficulties balancing the risks and benefits. Many factors, such as emerging drug resistance, side effects, cost and risk behavior need to be considered. This article aims to review antibiotic prophylaxis from the 1950s to 2000s, to describe the trend and reasons for different antibiotic use in each decade. We conclude that prophylactic antibiotics should be restricted to some high-risk travelers or short-term critical trips.
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spelling pubmed-62230762018-11-19 A review of antibiotic prophylaxis for traveler’s diarrhea: past to present Diptyanusa, Ajib Ngamprasertchai, Thundon Piyaphanee, Watcharapong Trop Dis Travel Med Vaccines Review As there is rapid increase in international travel to tropical and subtropical countries, there will likely be more people exposed to diarrheal pathogens in these moderate to high risk areas and subsequent increased concern for traveler’s diarrhea. The disease may appear as a mild clinical syndrome, yet a more debilitating presentation can lead to itinerary changes and hospitalization. As bacterial etiologies are the most common causative agents of TD, the use of antibiotic prophylaxis to prevent TD has been reported among travelers for several years. The most common type of antibiotic used for TD has changed over 50 years, depending on many influencing factors. The use of antibiotic prophylaxis for TD prevention in travelers is still controversial, mainly because of difficulties balancing the risks and benefits. Many factors, such as emerging drug resistance, side effects, cost and risk behavior need to be considered. This article aims to review antibiotic prophylaxis from the 1950s to 2000s, to describe the trend and reasons for different antibiotic use in each decade. We conclude that prophylactic antibiotics should be restricted to some high-risk travelers or short-term critical trips. BioMed Central 2018-11-07 /pmc/articles/PMC6223076/ /pubmed/30455974 http://dx.doi.org/10.1186/s40794-018-0074-4 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Diptyanusa, Ajib
Ngamprasertchai, Thundon
Piyaphanee, Watcharapong
A review of antibiotic prophylaxis for traveler’s diarrhea: past to present
title A review of antibiotic prophylaxis for traveler’s diarrhea: past to present
title_full A review of antibiotic prophylaxis for traveler’s diarrhea: past to present
title_fullStr A review of antibiotic prophylaxis for traveler’s diarrhea: past to present
title_full_unstemmed A review of antibiotic prophylaxis for traveler’s diarrhea: past to present
title_short A review of antibiotic prophylaxis for traveler’s diarrhea: past to present
title_sort review of antibiotic prophylaxis for traveler’s diarrhea: past to present
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223076/
https://www.ncbi.nlm.nih.gov/pubmed/30455974
http://dx.doi.org/10.1186/s40794-018-0074-4
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