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Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity

Inducers of satiety are drug targets for weight loss to mitigate obesity-associated diseases. Nucleobindin-2 (Nucb2) is thought to be post-translationally processed into bioactive nesfatin-1 peptide, which reportedly induces satiety, causes weight loss, and thus improves insulin sensitivity. Here, w...

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Detalles Bibliográficos
Autores principales: Ravussin, Anthony, Youm, Yun-Hee, Sander, Jil, Ryu, Seungjin, Nguyen, Kim, Varela, Luis, Suhlman, Gerald I., Sidorov, Sviatoslav, Horvath, Tamas L., Schultze, Joachim L., Dixit, Vishwa Deep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223120/
https://www.ncbi.nlm.nih.gov/pubmed/30067966
http://dx.doi.org/10.1016/j.celrep.2018.06.112