Cargando…

Data for the synthesis of new 4-aryloxy-N-arylanilines as potent succinate-cytochrome c reductase inhibitors

In this data article, we have designed a simple and facile protocol for copper-mediated synthesis of new 4-aryloxy-N-arylanilines under mild reaction conditions. The general information and synthetic procedures of all the target compounds were provided, and they were fully characterized by Nuclear M...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Hua, Song, Wei, Nie, Ren, Wang, Yu-Xia, Li, Hui-Lian, Jiang, Xiang-Sheng, Wu, Jun-Jun, Chen, Cheng, Wu, Qiong-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223225/
https://www.ncbi.nlm.nih.gov/pubmed/30426039
http://dx.doi.org/10.1016/j.dib.2018.10.059
_version_ 1783369374224089088
author Cheng, Hua
Song, Wei
Nie, Ren
Wang, Yu-Xia
Li, Hui-Lian
Jiang, Xiang-Sheng
Wu, Jun-Jun
Chen, Cheng
Wu, Qiong-You
author_facet Cheng, Hua
Song, Wei
Nie, Ren
Wang, Yu-Xia
Li, Hui-Lian
Jiang, Xiang-Sheng
Wu, Jun-Jun
Chen, Cheng
Wu, Qiong-You
author_sort Cheng, Hua
collection PubMed
description In this data article, we have designed a simple and facile protocol for copper-mediated synthesis of new 4-aryloxy-N-arylanilines under mild reaction conditions. The general information and synthetic procedures of all the target compounds were provided, and they were fully characterized by Nuclear Magnetic Resonance (NMR, including (1)H NMR and (13)C NMR), melting point measurements, and High-Resolution Mass Spectroscopy (HRMS). Furthermore, the inhibitory activities of these compounds against succinate-cytochrome c reductase (SCR) were evaluated, and the methods and procedures of enzyme inhibition experiments were also recorded in this data article. This article is related to “Synthesis of new 4-aryloxy-N-arylanilines and their inhibitory activities against succinate-cytochrome c reductase” (Cheng et al., 2018) [1].
format Online
Article
Text
id pubmed-6223225
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-62232252018-11-13 Data for the synthesis of new 4-aryloxy-N-arylanilines as potent succinate-cytochrome c reductase inhibitors Cheng, Hua Song, Wei Nie, Ren Wang, Yu-Xia Li, Hui-Lian Jiang, Xiang-Sheng Wu, Jun-Jun Chen, Cheng Wu, Qiong-You Data Brief Chemistry In this data article, we have designed a simple and facile protocol for copper-mediated synthesis of new 4-aryloxy-N-arylanilines under mild reaction conditions. The general information and synthetic procedures of all the target compounds were provided, and they were fully characterized by Nuclear Magnetic Resonance (NMR, including (1)H NMR and (13)C NMR), melting point measurements, and High-Resolution Mass Spectroscopy (HRMS). Furthermore, the inhibitory activities of these compounds against succinate-cytochrome c reductase (SCR) were evaluated, and the methods and procedures of enzyme inhibition experiments were also recorded in this data article. This article is related to “Synthesis of new 4-aryloxy-N-arylanilines and their inhibitory activities against succinate-cytochrome c reductase” (Cheng et al., 2018) [1]. Elsevier 2018-10-24 /pmc/articles/PMC6223225/ /pubmed/30426039 http://dx.doi.org/10.1016/j.dib.2018.10.059 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Chemistry
Cheng, Hua
Song, Wei
Nie, Ren
Wang, Yu-Xia
Li, Hui-Lian
Jiang, Xiang-Sheng
Wu, Jun-Jun
Chen, Cheng
Wu, Qiong-You
Data for the synthesis of new 4-aryloxy-N-arylanilines as potent succinate-cytochrome c reductase inhibitors
title Data for the synthesis of new 4-aryloxy-N-arylanilines as potent succinate-cytochrome c reductase inhibitors
title_full Data for the synthesis of new 4-aryloxy-N-arylanilines as potent succinate-cytochrome c reductase inhibitors
title_fullStr Data for the synthesis of new 4-aryloxy-N-arylanilines as potent succinate-cytochrome c reductase inhibitors
title_full_unstemmed Data for the synthesis of new 4-aryloxy-N-arylanilines as potent succinate-cytochrome c reductase inhibitors
title_short Data for the synthesis of new 4-aryloxy-N-arylanilines as potent succinate-cytochrome c reductase inhibitors
title_sort data for the synthesis of new 4-aryloxy-n-arylanilines as potent succinate-cytochrome c reductase inhibitors
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223225/
https://www.ncbi.nlm.nih.gov/pubmed/30426039
http://dx.doi.org/10.1016/j.dib.2018.10.059
work_keys_str_mv AT chenghua dataforthesynthesisofnew4aryloxynarylanilinesaspotentsuccinatecytochromecreductaseinhibitors
AT songwei dataforthesynthesisofnew4aryloxynarylanilinesaspotentsuccinatecytochromecreductaseinhibitors
AT nieren dataforthesynthesisofnew4aryloxynarylanilinesaspotentsuccinatecytochromecreductaseinhibitors
AT wangyuxia dataforthesynthesisofnew4aryloxynarylanilinesaspotentsuccinatecytochromecreductaseinhibitors
AT lihuilian dataforthesynthesisofnew4aryloxynarylanilinesaspotentsuccinatecytochromecreductaseinhibitors
AT jiangxiangsheng dataforthesynthesisofnew4aryloxynarylanilinesaspotentsuccinatecytochromecreductaseinhibitors
AT wujunjun dataforthesynthesisofnew4aryloxynarylanilinesaspotentsuccinatecytochromecreductaseinhibitors
AT chencheng dataforthesynthesisofnew4aryloxynarylanilinesaspotentsuccinatecytochromecreductaseinhibitors
AT wuqiongyou dataforthesynthesisofnew4aryloxynarylanilinesaspotentsuccinatecytochromecreductaseinhibitors