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HYCO-3, a dual CO-releaser/Nrf2 activator, reduces tissue inflammation in mice challenged with lipopolysaccharide

Oxidative stress and inflammation are predominant features of several chronic diseases. The nuclear factor erythroid 2-related factor 2 (Nrf2) is a major arbiter in counteracting these insults via up-regulation of several defensive proteins, including heme oxygenase-1 (HO-1). HO-1-derived carbon mon...

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Detalles Bibliográficos
Autores principales:	Motterlini, Roberto, Nikam, Aniket, Manin, Sylvie, Ollivier, Anthony, Wilson, Jayne Louise, Djouadi, Sabrina, Muchova, Lucie, Martens, Thierry, Rivard, Michael, Foresti, Roberta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223233/ https://www.ncbi.nlm.nih.gov/pubmed/30391826 http://dx.doi.org/10.1016/j.redox.2018.10.020

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