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The PARP1-Siah1 Axis Controls HIV-1 Transcription and Expression of Siah1 Substrates

Recentstudieshave revealeda keyrole ofPARP1that catalyzes the poly-ADP-ribosylation (PARylation) of substrates in regulating gene transcription. We show here that HIV-1 transcriptional activationalso requires PARP1 activity. Because efficient HIV-1 transactivation is knowntodependontheELL2-containin...

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Detalles Bibliográficos
Autores principales:	Yu, Dan, Liu, Rongdiao, Yang, Geng, Zhou, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223328/ https://www.ncbi.nlm.nih.gov/pubmed/29949759 http://dx.doi.org/10.1016/j.celrep.2018.05.084

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