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Multi-omics and temporal dynamics profiling reveal disruption of central metabolism in Helicobacter pylori on bismuth treatment
Integration of multi-omics enables uncovering cellular responses to stimuli or the mechanism of action of a drug at a system level. Bismuth drugs have long been used for the treatment of Helicobacter pylori infection and their antimicrobial activity was attributed to dysfunction of multiple proteins...
Autores principales: | Han, Bingjie, Zhang, Zhen, Xie, Yanxuan, Hu, Xuqiao, Wang, Haibo, Xia, Wei, Wang, Yulan, Li, Hongyan, Wang, Yuchuan, Sun, Hongzhe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223348/ https://www.ncbi.nlm.nih.gov/pubmed/30510674 http://dx.doi.org/10.1039/c8sc01668b |
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