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SciApps: a cloud-based platform for reproducible bioinformatics workflows
MOTIVATION: The rapid accumulation of both sequence and phenotype data generated by high-throughput methods has increased the need to store and analyze data on distributed storage and computing systems. Efficient data management across these heterogeneous systems requires a workflow management syste...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223375/ https://www.ncbi.nlm.nih.gov/pubmed/29897418 http://dx.doi.org/10.1093/bioinformatics/bty439 |
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author | Wang, Liya Lu, Zhenyuan Van Buren, Peter Ware, Doreen |
author_facet | Wang, Liya Lu, Zhenyuan Van Buren, Peter Ware, Doreen |
author_sort | Wang, Liya |
collection | PubMed |
description | MOTIVATION: The rapid accumulation of both sequence and phenotype data generated by high-throughput methods has increased the need to store and analyze data on distributed storage and computing systems. Efficient data management across these heterogeneous systems requires a workflow management system to simplify the task of analysis through automation and make large-scale bioinformatics analyses accessible and reproducible. RESULTS: We developed SciApps, a web-based platform for reproducible bioinformatics workflows. The platform is designed to automate the execution of modular Agave apps and support execution of workflows on local clusters or in a cloud. Two workflows, one for association and one for annotation, are provided as exemplar scientific use cases. AVAILABILITY AND IMPLEMENTATION: https://www.sciapps.org SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. |
format | Online Article Text |
id | pubmed-6223375 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-62233752018-11-14 SciApps: a cloud-based platform for reproducible bioinformatics workflows Wang, Liya Lu, Zhenyuan Van Buren, Peter Ware, Doreen Bioinformatics Applications Notes MOTIVATION: The rapid accumulation of both sequence and phenotype data generated by high-throughput methods has increased the need to store and analyze data on distributed storage and computing systems. Efficient data management across these heterogeneous systems requires a workflow management system to simplify the task of analysis through automation and make large-scale bioinformatics analyses accessible and reproducible. RESULTS: We developed SciApps, a web-based platform for reproducible bioinformatics workflows. The platform is designed to automate the execution of modular Agave apps and support execution of workflows on local clusters or in a cloud. Two workflows, one for association and one for annotation, are provided as exemplar scientific use cases. AVAILABILITY AND IMPLEMENTATION: https://www.sciapps.org SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2018-11-15 2018-06-12 /pmc/articles/PMC6223375/ /pubmed/29897418 http://dx.doi.org/10.1093/bioinformatics/bty439 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Applications Notes Wang, Liya Lu, Zhenyuan Van Buren, Peter Ware, Doreen SciApps: a cloud-based platform for reproducible bioinformatics workflows |
title | SciApps: a cloud-based platform for reproducible bioinformatics workflows |
title_full | SciApps: a cloud-based platform for reproducible bioinformatics workflows |
title_fullStr | SciApps: a cloud-based platform for reproducible bioinformatics workflows |
title_full_unstemmed | SciApps: a cloud-based platform for reproducible bioinformatics workflows |
title_short | SciApps: a cloud-based platform for reproducible bioinformatics workflows |
title_sort | sciapps: a cloud-based platform for reproducible bioinformatics workflows |
topic | Applications Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223375/ https://www.ncbi.nlm.nih.gov/pubmed/29897418 http://dx.doi.org/10.1093/bioinformatics/bty439 |
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