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SciApps: a cloud-based platform for reproducible bioinformatics workflows

MOTIVATION: The rapid accumulation of both sequence and phenotype data generated by high-throughput methods has increased the need to store and analyze data on distributed storage and computing systems. Efficient data management across these heterogeneous systems requires a workflow management syste...

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Detalles Bibliográficos
Autores principales: Wang, Liya, Lu, Zhenyuan, Van Buren, Peter, Ware, Doreen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223375/
https://www.ncbi.nlm.nih.gov/pubmed/29897418
http://dx.doi.org/10.1093/bioinformatics/bty439
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author Wang, Liya
Lu, Zhenyuan
Van Buren, Peter
Ware, Doreen
author_facet Wang, Liya
Lu, Zhenyuan
Van Buren, Peter
Ware, Doreen
author_sort Wang, Liya
collection PubMed
description MOTIVATION: The rapid accumulation of both sequence and phenotype data generated by high-throughput methods has increased the need to store and analyze data on distributed storage and computing systems. Efficient data management across these heterogeneous systems requires a workflow management system to simplify the task of analysis through automation and make large-scale bioinformatics analyses accessible and reproducible. RESULTS: We developed SciApps, a web-based platform for reproducible bioinformatics workflows. The platform is designed to automate the execution of modular Agave apps and support execution of workflows on local clusters or in a cloud. Two workflows, one for association and one for annotation, are provided as exemplar scientific use cases. AVAILABILITY AND IMPLEMENTATION: https://www.sciapps.org SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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spelling pubmed-62233752018-11-14 SciApps: a cloud-based platform for reproducible bioinformatics workflows Wang, Liya Lu, Zhenyuan Van Buren, Peter Ware, Doreen Bioinformatics Applications Notes MOTIVATION: The rapid accumulation of both sequence and phenotype data generated by high-throughput methods has increased the need to store and analyze data on distributed storage and computing systems. Efficient data management across these heterogeneous systems requires a workflow management system to simplify the task of analysis through automation and make large-scale bioinformatics analyses accessible and reproducible. RESULTS: We developed SciApps, a web-based platform for reproducible bioinformatics workflows. The platform is designed to automate the execution of modular Agave apps and support execution of workflows on local clusters or in a cloud. Two workflows, one for association and one for annotation, are provided as exemplar scientific use cases. AVAILABILITY AND IMPLEMENTATION: https://www.sciapps.org SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2018-11-15 2018-06-12 /pmc/articles/PMC6223375/ /pubmed/29897418 http://dx.doi.org/10.1093/bioinformatics/bty439 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Notes
Wang, Liya
Lu, Zhenyuan
Van Buren, Peter
Ware, Doreen
SciApps: a cloud-based platform for reproducible bioinformatics workflows
title SciApps: a cloud-based platform for reproducible bioinformatics workflows
title_full SciApps: a cloud-based platform for reproducible bioinformatics workflows
title_fullStr SciApps: a cloud-based platform for reproducible bioinformatics workflows
title_full_unstemmed SciApps: a cloud-based platform for reproducible bioinformatics workflows
title_short SciApps: a cloud-based platform for reproducible bioinformatics workflows
title_sort sciapps: a cloud-based platform for reproducible bioinformatics workflows
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223375/
https://www.ncbi.nlm.nih.gov/pubmed/29897418
http://dx.doi.org/10.1093/bioinformatics/bty439
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