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A one year audit of patients with venous thromboembolism presenting to a tertiary hospital in Johannesburg, South Africa

INTRODUCTION: Given the growing burden of venous thromboembolism (VTE) worldwide and the paucity of data from the developing world, the aim of this study was to audit the characteristics, risk factors and length of hospital stay of patients with VTE presenting to a tertiary hospital emergency centre...

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Autores principales: Goldstein, Lara Nicole, Wu, Ming-Tung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: African Federation for Emergency Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223590/
https://www.ncbi.nlm.nih.gov/pubmed/30456139
http://dx.doi.org/10.1016/j.afjem.2017.08.006
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author Goldstein, Lara Nicole
Wu, Ming-Tung
author_facet Goldstein, Lara Nicole
Wu, Ming-Tung
author_sort Goldstein, Lara Nicole
collection PubMed
description INTRODUCTION: Given the growing burden of venous thromboembolism (VTE) worldwide and the paucity of data from the developing world, the aim of this study was to audit the characteristics, risk factors and length of hospital stay of patients with VTE presenting to a tertiary hospital emergency centre in Johannesburg, South Africa. METHODS: The study was a retrospective record review of all patients who presented with VTE to a tertiary academic emergency centre in Johannesburg, South Africa from 1 April 2012 to 30 March 2013. RESULTS: Venous thromboembolism was identified in 74 patients; 56 (75.7%) with isolated deep vein thrombosis, 13 (17.6%) with pulmonary embolism and five (6.8%) who had a concurrent deep vein thrombosis with pulmonary embolism. The median age of the patients was 40 years old (range 19–90). The female to male ratio was 2:1. HIV infection, tuberculosis and history of immobilisation were the most common risk factors. The median duration of hospital stay was 14 days (range 4–36). A therapeutic International Normalised Ratio at discharge was only reached in 36.5% of patients. CONCLUSION: Venous thromboembolism presentation to the emergency centre is not common, but the risks associated with the morbidity and mortality related to it makes it important despite its relative scarcity. The prevalence of HIV infection amongst patients with VTE is concerning – not only related to the frequency of the pathology but also due to HIV not being factored into the common VTE risk stratification scores.
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spelling pubmed-62235902018-11-19 A one year audit of patients with venous thromboembolism presenting to a tertiary hospital in Johannesburg, South Africa Goldstein, Lara Nicole Wu, Ming-Tung Afr J Emerg Med Original Article INTRODUCTION: Given the growing burden of venous thromboembolism (VTE) worldwide and the paucity of data from the developing world, the aim of this study was to audit the characteristics, risk factors and length of hospital stay of patients with VTE presenting to a tertiary hospital emergency centre in Johannesburg, South Africa. METHODS: The study was a retrospective record review of all patients who presented with VTE to a tertiary academic emergency centre in Johannesburg, South Africa from 1 April 2012 to 30 March 2013. RESULTS: Venous thromboembolism was identified in 74 patients; 56 (75.7%) with isolated deep vein thrombosis, 13 (17.6%) with pulmonary embolism and five (6.8%) who had a concurrent deep vein thrombosis with pulmonary embolism. The median age of the patients was 40 years old (range 19–90). The female to male ratio was 2:1. HIV infection, tuberculosis and history of immobilisation were the most common risk factors. The median duration of hospital stay was 14 days (range 4–36). A therapeutic International Normalised Ratio at discharge was only reached in 36.5% of patients. CONCLUSION: Venous thromboembolism presentation to the emergency centre is not common, but the risks associated with the morbidity and mortality related to it makes it important despite its relative scarcity. The prevalence of HIV infection amongst patients with VTE is concerning – not only related to the frequency of the pathology but also due to HIV not being factored into the common VTE risk stratification scores. African Federation for Emergency Medicine 2018-03 2017-09-22 /pmc/articles/PMC6223590/ /pubmed/30456139 http://dx.doi.org/10.1016/j.afjem.2017.08.006 Text en © 2018 African Federation for Emergency Medicine. Publishing services provided by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Goldstein, Lara Nicole
Wu, Ming-Tung
A one year audit of patients with venous thromboembolism presenting to a tertiary hospital in Johannesburg, South Africa
title A one year audit of patients with venous thromboembolism presenting to a tertiary hospital in Johannesburg, South Africa
title_full A one year audit of patients with venous thromboembolism presenting to a tertiary hospital in Johannesburg, South Africa
title_fullStr A one year audit of patients with venous thromboembolism presenting to a tertiary hospital in Johannesburg, South Africa
title_full_unstemmed A one year audit of patients with venous thromboembolism presenting to a tertiary hospital in Johannesburg, South Africa
title_short A one year audit of patients with venous thromboembolism presenting to a tertiary hospital in Johannesburg, South Africa
title_sort one year audit of patients with venous thromboembolism presenting to a tertiary hospital in johannesburg, south africa
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223590/
https://www.ncbi.nlm.nih.gov/pubmed/30456139
http://dx.doi.org/10.1016/j.afjem.2017.08.006
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