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Radiolabeled F(ab′)(2)-cetuximab for theranostic purposes in colorectal and skin tumor-bearing mice models

PURPOSE: This study aimed to investigate theranostic strategies in colorectal and skin cancer based on fragments of cetuximab, an anti-EGFR mAb, labeled with radionuclide with imaging and therapeutic properties, (111)In and (177)Lu, respectively. METHODS: We designed F(ab′)(2)-fragments of cetuximab...

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Detalles Bibliográficos
Autores principales:	Bellaye, P.-S., Moreau, M., Raguin, O., Oudot, A., Bernhard, C., Vrigneaud, J.-M., Dumont, L., Vandroux, D., Denat, F., Cochet, A., Brunotte, F., Collin, B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223717/ https://www.ncbi.nlm.nih.gov/pubmed/29777377 http://dx.doi.org/10.1007/s12094-018-1886-4

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