Secretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells

In Parkinson’s disease and other Lewy body disorders, the propagation of pathology has been accredited to the spreading of extracellular α-synuclein (α-syn). Although the pathogenic mechanisms are not fully understood, cell-to-cell transfer of α-syn via exosomes and other extracellular vesicles (EVs...

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Detalles Bibliográficos
Autores principales: Gustafsson, Gabriel, Lööv, Camilla, Persson, Emma, Lázaro, Diana F., Takeda, Shuko, Bergström, Joakim, Erlandsson, Anna, Sehlin, Dag, Balaj, Leonora, György, Bence, Hallbeck, Martin, Outeiro, Tiago F., Breakefield, Xandra O., Hyman, Bradley T., Ingelsson, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223723/
https://www.ncbi.nlm.nih.gov/pubmed/30288631
http://dx.doi.org/10.1007/s10571-018-0622-5

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