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Anti-EGFR anchored paclitaxel loaded PLGA nanoparticles for the treatment of triple negative breast cancer. In-vitro and in-vivo anticancer activities

The aim of the present study is to analyze the viability of anti-EGFR anchored immunonanoparticle (INP) bearing Paclitaxel (PTX) to specifically bind the EGFR protein on the TNBC cells. The NP was prepared by nanoprecipitation and characterized the particle size, charge, entrapment of drug and relea...

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Detalles Bibliográficos
Autores principales:	Venugopal, Vijayan, Krishnan, Shalini, Palanimuthu, Vasanth Raj, Sankarankutty, Subin, Kalaimani, Jayaraja Kumar, Karupiah, Sundram, Kit, Ng Siew, Hock, Tang Thean
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224030/ https://www.ncbi.nlm.nih.gov/pubmed/30408068 http://dx.doi.org/10.1371/journal.pone.0206109

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