A simian-adenovirus-vectored rabies vaccine suitable for thermostabilisation and clinical development for low-cost single-dose pre-exposure prophylaxis

BACKGROUND: Estimates of current global rabies mortality range from 26,000 to 59,000 deaths per annum. Although pre-exposure prophylaxis using inactivated rabies virus vaccines (IRVs) is effective, it requires two to three doses and is regarded as being too expensive and impractical for inclusion in...

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Detalles Bibliográficos
Autores principales: Wang, Chuan, Dulal, Pawan, Zhou, Xiangyang, Xiang, Zhiquan, Goharriz, Hooman, Banyard, Ashley, Green, Nicky, Brunner, Livia, Ventura, Roland, Collin, Nicolas, Draper, Simon J., Hill, Adrian V. S., Ashfield, Rebecca, Fooks, Anthony R., Ertl, Hildegund C., Douglas, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224154/
https://www.ncbi.nlm.nih.gov/pubmed/30372438
http://dx.doi.org/10.1371/journal.pntd.0006870

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