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Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resistance to benzimidazoles

Benzimidazoles (BZ) are essential components of the limited chemotherapeutic arsenal available to control the global burden of parasitic nematodes. The emerging threat of BZ resistance among multiple nematode species necessitates the development of novel strategies to identify genetic and molecular...

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Detalles Bibliográficos
Autores principales:	Hahnel, Steffen R., Zdraljevic, Stefan, Rodriguez, Briana C., Zhao, Yuehui, McGrath, Patrick T., Andersen, Erik C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224181/ https://www.ncbi.nlm.nih.gov/pubmed/30372484 http://dx.doi.org/10.1371/journal.ppat.1007226

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