Environmental toxicant induced epigenetic transgenerational inheritance of ovarian pathology and granulosa cell epigenome and transcriptome alterations: ancestral origins of polycystic ovarian syndrome and primary ovarian insufiency

Two of the most prevalent ovarian diseases affecting women’s fertility and health are Primary Ovarian Insufficiency (POI) and Polycystic Ovarian Syndrome (PCOS). Previous studies have shown that exposure to a number of environmental toxicants can promote the epigenetic transgenerational inheritance...

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Detalles Bibliográficos
Autores principales: Nilsson, Eric, Klukovich, Rachel, Sadler-Riggleman, Ingrid, Beck, Daniel, Xie, Yeming, Yan, Wei, Skinner, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224216/
https://www.ncbi.nlm.nih.gov/pubmed/30207508
http://dx.doi.org/10.1080/15592294.2018.1521223

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