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Sirtuin 1 genetic variation, energy balance and colorectal cancer risk by sex and subsite in the Netherlands Cohort Study

Sirtuin 1 (SIRT1) is an energy-sensing protein, which may affect tumorigenesis. We used SIRT1 variants as time-independent indicators of SIRT1 involvement in carcinogenesis and we studied two tagging SIRT1 variants in relation to colorectal cancer (CRC) risk. We also evaluated known energy balance-r...

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Detalles Bibliográficos
Autores principales:	Simons, C. C. J. M., Schouten, L. J., Godschalk, R. W., van Schooten, F. J., van den Brandt, P. A., Weijenberg, M. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224413/ https://www.ncbi.nlm.nih.gov/pubmed/30410074 http://dx.doi.org/10.1038/s41598-018-34728-6

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