Depletion of regulatory T cells in ongoing paracoccidioidomycosis rescues protective Th1/Th17 immunity and prevents fatal disease outcome

In human paracoccidioidomycosis (PCM), a primary fungal infection typically diagnosed when the disease is already established, regulatory T cells (Treg) cells are associated with disease severity. Experimental studies in pulmonary PCM confirmed the detrimental role of these cells, but in most studie...

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Detalles Bibliográficos
Autores principales: Galdino, Nayane A. L., Loures, Flávio V., de Araújo, Eliseu F., da Costa, Tania A., Preite, Nycolas W., Calich, Vera Lúcia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224548/
https://www.ncbi.nlm.nih.gov/pubmed/30410119
http://dx.doi.org/10.1038/s41598-018-35037-8

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