Self-Assembly of the RZZ Complex into Filaments Drives Kinetochore Expansion in the Absence of Microtubule Attachment

The kinetochore is a dynamic multi-protein assembly that forms on each sister chromatid and interacts with microtubules of the mitotic spindle to drive chromosome segregation. In animals, kinetochores without attached microtubules expand their outermost layer into crescent and ring shapes to promote...

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Detalles Bibliográficos
Autores principales: Pereira, Cláudia, Reis, Rita M., Gama, José B., Celestino, Ricardo, Cheerambathur, Dhanya K., Carvalho, Ana X., Gassmann, Reto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224608/
https://www.ncbi.nlm.nih.gov/pubmed/30415699
http://dx.doi.org/10.1016/j.cub.2018.08.056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224608/
https://www.ncbi.nlm.nih.gov/pubmed/30415699
http://dx.doi.org/10.1016/j.cub.2018.08.056

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