Cargando…

Structural basis for the recognition of sulfur in phosphorothioated DNA

There have been very few reports on protein domains that specifically recognize sulfur. Here we present the crystal structure of the sulfur-binding domain (SBD) from the DNA phosphorothioation (PT)-dependent restriction endonuclease ScoMcrA. SBD contains a hydrophobic surface cavity that is formed b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Guang, Fu, Wencheng, Zhang, Zhenyi, He, Yao, Yu, Hao, Wang, Yuli, Wang, Xiaolei, Zhao, Yi-Lei, Deng, Zixin, Wu, Geng, He, Xinyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224610/ https://www.ncbi.nlm.nih.gov/pubmed/30409991 http://dx.doi.org/10.1038/s41467-018-07093-1

Ejemplares similares

Crystal Structure of the Cysteine Desulfurase DndA from Streptomyces lividans Which Is Involved in DNA Phosphorothioation
por: Chen, Fukun, et al.
Publicado: (2012)

dndDB: A Database Focused on Phosphorothioation of the DNA Backbone
por: Ou, Hong-Yu, et al.
Publicado: (2009)

Phosphorothioate DNA as an antioxidant in bacteria
por: Xie, Xinqiang, et al.
Publicado: (2012)

Cleavage of Phosphorothioated DNA and Methylated DNA by the Type IV Restriction Endonuclease ScoMcrA
por: Liu, Guang, et al.
Publicado: (2010)

DNA backbone interactions impact the sequence specificity of DNA sulfur-binding domains: revelations from structural analyses
por: Yu, Hao, et al.
Publicado: (2020)

DNA phosphorothioation in Streptomyces lividans: mutational analysis of the dnd locus
por: Xu, Tiegang, et al.
Publicado: (2009)

DNA Phosphorothioate Modification Plays a Role in Peroxides Resistance in Streptomyces lividans
por: Dai, Daofeng, et al.
Publicado: (2016)

DNA modification by sulfur: analysis of the sequence recognition specificity surrounding the modification sites
por: Liang, Jingdan, et al.
Publicado: (2007)

Mechanistic Investigation on ROS Resistance of Phosphorothioated DNA
por: Wu, Tingting, et al.
Publicado: (2017)

Origin of iodine preferential attack at sulfur in phosphorothioate and subsequent P-O or P-S bond dissociation
por: Huang, Qiang, et al.
Publicado: (2022)

Interactions of Dnd proteins involved in bacterial DNA phosphorothioate modification
por: Xiong, Wei, et al.
Publicado: (2015)

The origin and impeded dissemination of the DNA phosphorothioation system in prokaryotes
por: Jian, Huahua, et al.
Publicado: (2021)

Single-molecule optical mapping of the distribution of DNA phosphorothioate epigenetics
por: Wei, Yue, et al.
Publicado: (2021)

Structural and Functional Analysis of DndE Involved in DNA Phosphorothioation in the Haloalkaliphilic Archaea Natronorubrum bangense JCM10635
por: He, Wei, et al.
Publicado: (2022)

Characterization of a promiscuous DNA sulfur binding domain and application in site-directed RNA base editing
por: Hu, Wenyue, et al.
Publicado: (2023)

A rapid nucleic acid detection platform based on phosphorothioate-DNA and sulfur binding domain
por: Shuai, Yuting, et al.
Publicado: (2023)

A new type of DNA phosphorothioation-based antiviral system in archaea
por: Xiong, Lei, et al.
Publicado: (2019)

Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE
por: Gao, Haiyan, et al.
Publicado: (2022)

DNA Phosphorothioate Modifications Are Widely Distributed in the Human Microbiome
por: Sun, Yihua, et al.
Publicado: (2020)

DNA phosphorothioate modification—a new multi-functional epigenetic system in bacteria
por: Wang, Lianrong, et al.
Publicado: (2018)

A Novel Target of IscS in Escherichia coli: Participating in DNA Phosphorothioation
por: An, Xianhui, et al.
Publicado: (2012)

Sulfur-centered hemi-bond radicals as active intermediates in S-DNA phosphorothioate oxidation
por: Jie, Jialong, et al.
Publicado: (2019)

DNA phosphorothioate modifications influence the global transcriptional response and protect DNA from double-stranded breaks
por: Gan, Rui, et al.
Publicado: (2014)

Structural Analysis of an l-Cysteine Desulfurase from an Ssp DNA Phosphorothioation System
por: Liu, Liqiong, et al.
Publicado: (2020)

In Vivo Mutational Characterization of DndE Involved in DNA Phosphorothioate Modification
por: Lai, Chongde, et al.
Publicado: (2014)

Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity
por: Huang, Qiang, et al.
Publicado: (2021)

Quantitative mapping of DNA phosphorothioatome reveals phosphorothioate heterogeneity of low modification frequency
por: Li, Jinli, et al.
Publicado: (2019)

Author Correction: Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity
por: Huang, Qiang, et al.
Publicado: (2021)

In vitro analysis of phosphorothioate modification of DNA reveals substrate recognition by a multiprotein complex
por: Cao, Bo, et al.
Publicado: (2015)

Controlled sulfur-based engineering confers mouldability to phosphorothioate antisense oligonucleotides
por: Genna, Vito, et al.
Publicado: (2023)

Development of Phosphorothioate DNA and DNA Thioaptamers
por: Volk, David E., et al.
Publicado: (2017)

Involvement of the DNA Phosphorothioation System in TorR Binding and Anaerobic TMAO Respiration in Salmonella enterica
por: Tang, You, et al.
Publicado: (2022)

Regulation of DNA phosphorothioate modification in Salmonella enterica by DndB
por: He, Wei, et al.
Publicado: (2015)

Structural investigation into physiological DNA phosphorothioate modification
por: Lan, Wenxian, et al.
Publicado: (2016)

SspABCD-SspFGH Constitutes a New Type of DNA Phosphorothioate-Based Bacterial Defense System
por: Wang, Shiwei, et al.
Publicado: (2021)

Mixed-Sequence Recognition of Double-Stranded DNA Using Enzymatically Stable Phosphorothioate Invader Probes
por: Anderson, Brooke A., et al.
Publicado: (2015)

Novel Iodine-induced Cleavage Real-time PCR Assay for Accurate Quantification of Phosphorothioate Modified Sites in Bacterial DNA
por: Chen, Yi, et al.
Publicado: (2019)

Development of Methods Derived from Iodine-Induced Specific Cleavage for Identification and Quantitation of DNA Phosphorothioate Modifications
por: Zhu, Sucheng, et al.
Publicado: (2020)

Recognition and cleavage of 5-methylcytosine DNA by bacterial SRA-HNH proteins
por: Han, Tiesheng, et al.
Publicado: (2015)

Selective Covalent Conjugation of Phosphorothioate DNA Oligonucleotides with Streptavidin
por: Rabe, Kersten S., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_1c8v2rksldser2ts36pi28h1t0