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Effect of PF-04634817, an Oral CCR2/5 Chemokine Receptor Antagonist, on Albuminuria in Adults with Overt Diabetic Nephropathy

INTRODUCTION: Inflammatory cell recruitment, which is potentially mediated by the monocyte chemoattractant protein 1/C-C chemokine receptor type 2 (CCR2) system and by C-C chemokine receptor type 5 (CCR5) activity, may play a role in the development and progression of diabetic nephropathy. PF-046348...

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Detalles Bibliográficos
Autores principales:	Gale, Jeremy D., Gilbert, Steven, Blumenthal, Samuel, Elliott, Tom, Pergola, Pablo E., Goteti, Kosalaram, Scheele, Wim, Perros-Huguet, Christelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224665/ https://www.ncbi.nlm.nih.gov/pubmed/30450458 http://dx.doi.org/10.1016/j.ekir.2018.07.010

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