Identification of key pathways and metabolic fingerprints of longevity in C. elegans

Impaired insulin/IGF-1 signaling (IIS) and caloric restriction (CR) prolong lifespan in the nematode C. elegans. However, a cross comparison of these longevity pathways using a multi-omics integration approach is lacking. In this study, we aimed to identify key pathways and metabolite fingerprints o...

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Detalles Bibliográficos
Autores principales: Gao, Arwen W., Smith, Reuben L., van Weeghel, Michel, Kamble, Rashmi, Janssens, Georges E., Houtkooper, Riekelt H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224709/
https://www.ncbi.nlm.nih.gov/pubmed/30300667
http://dx.doi.org/10.1016/j.exger.2018.10.003

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