Synthesis and Pharmacological Evaluation of Novel Silodosin-Based Arylsulfonamide Derivatives as α(1A)/α(1D)-Adrenergic Receptor Antagonist with Potential Uroselective Profile

Benign prostatic hyperplasia (BPH) is the most common male clinical problem impacting the quality of life of older men. Clinical studies have indicated that the inhibition of α(1A)-/α(1D) adrenoceptors might offer effective therapy in lower urinary tract symptoms. Herein, a limited series of arylsul...

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Detalles Bibliográficos
Autores principales: Canale, Vittorio, Rak, Aleksandra, Kotańska, Magdalena, Knutelska, Joanna, Siwek, Agata, Bednarski, Marek, Nowiński, Leszek, Zygmunt, Małgorzata, Koczurkiewicz, Paulina, Pękala, Elżbieta, Sapa, Jacek, Zajdel, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225212/
https://www.ncbi.nlm.nih.gov/pubmed/30158432
http://dx.doi.org/10.3390/molecules23092175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225212/
https://www.ncbi.nlm.nih.gov/pubmed/30158432
http://dx.doi.org/10.3390/molecules23092175

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