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Synthesis and Pharmacological Evaluation of Novel Silodosin-Based Arylsulfonamide Derivatives as α(1A)/α(1D)-Adrenergic Receptor Antagonist with Potential Uroselective Profile
Benign prostatic hyperplasia (BPH) is the most common male clinical problem impacting the quality of life of older men. Clinical studies have indicated that the inhibition of α(1A)-/α(1D) adrenoceptors might offer effective therapy in lower urinary tract symptoms. Herein, a limited series of arylsul...
Autores principales: | Canale, Vittorio, Rak, Aleksandra, Kotańska, Magdalena, Knutelska, Joanna, Siwek, Agata, Bednarski, Marek, Nowiński, Leszek, Zygmunt, Małgorzata, Koczurkiewicz, Paulina, Pękala, Elżbieta, Sapa, Jacek, Zajdel, Paweł |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225212/ https://www.ncbi.nlm.nih.gov/pubmed/30158432 http://dx.doi.org/10.3390/molecules23092175 |
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