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Simultaneous Determination of Aesculin, Aesculetin, Fraxetin, Fraxin and Polydatin in Beagle Dog Plasma by UPLC-ESI-MS/MS and Its Application in a Pharmacokinetic Study after Oral Administration Extracts of Ledum palustre L.

A rapid, simple and sensitive ultra-performance liquid chromatography-electrospray-ionization-tandem mass spectrometry (UPLC-ESI-MS/MS) method was developed and validated for the simultaneous determination of aesculin, aesculetin, fraxetin, fraxin and polydatin in beagle dog plasma for the first tim...

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Detalles Bibliográficos
Autores principales:	Wang, Zhibin, Zhu, Wenbo, Liu, Hua, Wu, Gaosong, Song, Mengmeng, Yang, Bingyou, Yang, Deqiang, Wang, Qiuhong, Kuang, Haixue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225292/ https://www.ncbi.nlm.nih.gov/pubmed/30205426 http://dx.doi.org/10.3390/molecules23092285

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