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Structure-Based Discovery and Synthesis of Potential Transketolase Inhibitors
Transketolase (TKL) plays a key role in plant photosynthesis and has been predicted to be a potent herbicide target. Homology modeling and molecular dynamics simulation were used to construct a target protein model. A target-based virtual screening was developed to discover novel potential transketo...
Autores principales: | Huo, Jingqian, Zhao, Bin, Zhang, Zhe, Xing, Jihong, Zhang, Jinlin, Dong, Jingao, Fan, Zhijin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225308/ https://www.ncbi.nlm.nih.gov/pubmed/30142874 http://dx.doi.org/10.3390/molecules23092116 |
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