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Direct Observation of Murine Prion Protein Replication in Vitro
[Image: see text] Prions are believed to propagate when an assembly of prion protein (PrP) enters a cell and replicates to produce two or more fibrils, leading to an exponential increase in PrP aggregate number with time. However, the molecular basis of this process has not yet been established in d...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225343/ https://www.ncbi.nlm.nih.gov/pubmed/30351023 http://dx.doi.org/10.1021/jacs.8b08311 |