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Direct Observation of Murine Prion Protein Replication in Vitro

[Image: see text] Prions are believed to propagate when an assembly of prion protein (PrP) enters a cell and replicates to produce two or more fibrils, leading to an exponential increase in PrP aggregate number with time. However, the molecular basis of this process has not yet been established in d...

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Detalles Bibliográficos
Autores principales:	Sang, Jason C., Meisl, Georg, Thackray, Alana M., Hong, Liu, Ponjavic, Aleks, Knowles, Tuomas P. J., Bujdoso, Raymond, Klenerman, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225343/ https://www.ncbi.nlm.nih.gov/pubmed/30351023 http://dx.doi.org/10.1021/jacs.8b08311

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