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Identification of Nucleophilic Probes for Protease-Mediated Transpeptidation
Proteases have evolved to mediate the hydrolysis of peptide bonds but may perform transpeptidation in the presence of a proper nucleophilic molecule that can effectively compete with water to react with the acyl-enzyme intermediate. There have been several examples of protease-mediated transpeptidat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225416/ https://www.ncbi.nlm.nih.gov/pubmed/30131476 http://dx.doi.org/10.3390/molecules23092109 |