Cargando…
Involvement of Up-Regulation of DR5 Expression and Down-Regulation of c-FLIP in Niclosamide-Mediated TRAIL Sensitization in Human Renal Carcinoma Caki Cells
Niclosamide is used to treat intestinal parasite infections, as being an anthelmintic drug. Recently, several papers suggest the niclosamide inhibits multiple signaling pathways, which are highly activated and mutated in cancer. Here, niclosamide was evaluated for identifying strategies to overcome...
Autores principales: | Yun, Jeong Mi, Woo, Seon Min, Seo, Seung Un, Min, Kyoung-Jin, Kim, Dong Eun, Kwon, Taeg Kyu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225471/ https://www.ncbi.nlm.nih.gov/pubmed/30189637 http://dx.doi.org/10.3390/molecules23092264 |
Ejemplares similares
-
Volasertib Enhances Sensitivity to TRAIL in Renal Carcinoma Caki Cells through Downregulation of c-FLIP Expression
por: Jeon, Mi-Yeon, et al.
Publicado: (2017) -
YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-κB-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cells
por: Woo, Seon Min, et al.
Publicado: (2016) -
BIX-01294 sensitizes renal cancer Caki cells to TRAIL-induced apoptosis through downregulation of survivin expression and upregulation of DR5 expression
por: Woo, Seon Min, et al.
Publicado: (2018) -
Garcinol Enhances TRAIL-Induced Apoptotic Cell Death through Up-Regulation of DR5 and Down-Regulation of c-FLIP Expression
por: Kim, Seok, et al.
Publicado: (2018) -
Eupafolin enhances TRAIL-mediated apoptosis through cathepsin S-induced down-regulation of Mcl-1 expression and AMPK-mediated Bim up-regulation in renal carcinoma Caki cells
por: Han, Min Ae, et al.
Publicado: (2016)