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Computational screening of chalcones acting against topoisomerase IIα and their cytotoxicity towards cancer cell lines

Targeted cancer therapy has become one of the high potential cancer treatments. Human topoisomerase II (hTopoII), which catalyzes the cleavage and rejoining of double-stranded DNA, is an important molecular target for the development of novel cancer therapeutics. In order to diversify the pharmacolo...

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Detalles Bibliográficos
Autores principales:	Sangpheak, Kanyani, Mueller, Monika, Darai, Nitchakan, Wolschann, Peter, Suwattanasophon, Chonticha, Ruga, Ritbey, Chavasiri, Warinthon, Seetaha, Supaporn, Choowongkomon, Kiattawee, Kungwan, Nawee, Rungnim, Chompoonut, Rungrotmongkol, Thanyada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225485/ https://www.ncbi.nlm.nih.gov/pubmed/30394113 http://dx.doi.org/10.1080/14756366.2018.1507029

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