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Improved xylose tolerance and 2,3-butanediol production of Klebsiella pneumoniae by directed evolution of rpoD and the mechanisms revealed by transcriptomics

BACKGROUND: The biological production of 2,3-butanediol from xylose-rich raw materials from Klebsiella pneumoniae is a low-cost process. RpoD, an encoding gene of the sigma factor, is the key element in global transcription machinery engineering and has been successfully used to improve the fermenta...

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Detalles Bibliográficos
Autores principales:	Guo, Xue-Wu, Zhang, Yu, Li, Lu-Lu, Guan, Xiang-Yu, Guo, Jian, Wu, De-Guang, Chen, Ye-Fu, Xiao, Dong-Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225576/ https://www.ncbi.nlm.nih.gov/pubmed/30455736 http://dx.doi.org/10.1186/s13068-018-1312-8

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