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Identification of Pen m 4 as a potential cause of occupational asthma to Gammarus shrimp

We present the case of a 34-year-old male patient employed for 8 years in a company manufacturing and packaging animal feed. The patient developed occupational asthma to dry Gammarus powder. The diagnosis was confirmed by specific bronchial provocation test. The determination of specific IgE antibod...

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Autores principales: Sogo, A., Cruz, M. J., Amengual, M. J., Muñoz, X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225630/
https://www.ncbi.nlm.nih.gov/pubmed/30455865
http://dx.doi.org/10.1186/s13601-018-0232-9
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author Sogo, A.
Cruz, M. J.
Amengual, M. J.
Muñoz, X.
author_facet Sogo, A.
Cruz, M. J.
Amengual, M. J.
Muñoz, X.
author_sort Sogo, A.
collection PubMed
description We present the case of a 34-year-old male patient employed for 8 years in a company manufacturing and packaging animal feed. The patient developed occupational asthma to dry Gammarus powder. The diagnosis was confirmed by specific bronchial provocation test. The determination of specific IgE antibodies was positive for Pen m 4, a sarcoplasmic calcium binding protein, with a level of 6.7 ISU-E. The sensitization to Pen m 4 described here may identify a new allergen causing occupational asthma in these workers.
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spelling pubmed-62256302018-11-19 Identification of Pen m 4 as a potential cause of occupational asthma to Gammarus shrimp Sogo, A. Cruz, M. J. Amengual, M. J. Muñoz, X. Clin Transl Allergy Letter to the Editor We present the case of a 34-year-old male patient employed for 8 years in a company manufacturing and packaging animal feed. The patient developed occupational asthma to dry Gammarus powder. The diagnosis was confirmed by specific bronchial provocation test. The determination of specific IgE antibodies was positive for Pen m 4, a sarcoplasmic calcium binding protein, with a level of 6.7 ISU-E. The sensitization to Pen m 4 described here may identify a new allergen causing occupational asthma in these workers. BioMed Central 2018-11-09 /pmc/articles/PMC6225630/ /pubmed/30455865 http://dx.doi.org/10.1186/s13601-018-0232-9 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Sogo, A.
Cruz, M. J.
Amengual, M. J.
Muñoz, X.
Identification of Pen m 4 as a potential cause of occupational asthma to Gammarus shrimp
title Identification of Pen m 4 as a potential cause of occupational asthma to Gammarus shrimp
title_full Identification of Pen m 4 as a potential cause of occupational asthma to Gammarus shrimp
title_fullStr Identification of Pen m 4 as a potential cause of occupational asthma to Gammarus shrimp
title_full_unstemmed Identification of Pen m 4 as a potential cause of occupational asthma to Gammarus shrimp
title_short Identification of Pen m 4 as a potential cause of occupational asthma to Gammarus shrimp
title_sort identification of pen m 4 as a potential cause of occupational asthma to gammarus shrimp
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225630/
https://www.ncbi.nlm.nih.gov/pubmed/30455865
http://dx.doi.org/10.1186/s13601-018-0232-9
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