The polyphenol quercetin induces cell death in leukemia by targeting epigenetic regulators of pro-apoptotic genes

BACKGROUND: In the present study, we investigated the molecular mechanisms underlying the pro-apoptotic effects of quercetin (Qu) by evaluating the effect of Qu treatment on DNA methylation and posttranslational histone modifications of genes related to the apoptosis pathway. This study was performe...

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Detalles Bibliográficos
Autores principales: Alvarez, Marisa Claudia, Maso, Victor, Torello, Cristiane Okuda, Ferro, Karla Priscilla, Saad, Sara Teresinha Olalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225654/
https://www.ncbi.nlm.nih.gov/pubmed/30409182
http://dx.doi.org/10.1186/s13148-018-0563-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225654/
https://www.ncbi.nlm.nih.gov/pubmed/30409182
http://dx.doi.org/10.1186/s13148-018-0563-3

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