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The polyphenol quercetin induces cell death in leukemia by targeting epigenetic regulators of pro-apoptotic genes
BACKGROUND: In the present study, we investigated the molecular mechanisms underlying the pro-apoptotic effects of quercetin (Qu) by evaluating the effect of Qu treatment on DNA methylation and posttranslational histone modifications of genes related to the apoptosis pathway. This study was performe...
Autores principales: | Alvarez, Marisa Claudia, Maso, Victor, Torello, Cristiane Okuda, Ferro, Karla Priscilla, Saad, Sara Teresinha Olalla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225654/ https://www.ncbi.nlm.nih.gov/pubmed/30409182 http://dx.doi.org/10.1186/s13148-018-0563-3 |
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