Immunomodulatory effects of intraoperative dexmedetomidine on T helper 1, T helper 2, T helper 17 and regulatory T cells cytokine levels and their balance: a prospective, randomised, double-blind, dose-response clinical study

BACKGROUND: The ratio of T helper 1 (Th1) to T helper 2 (Th2) as well as T helper 17 (Th17) to regulatory T cells (Treg) represents the state and direction of immune response. Recent studies demonstrated that dexmedetomidine reduced the secretion of inflammatory cytokines. We performed this study to...

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Detalles Bibliográficos
Autores principales: Lee, Jae-Myeong, Han, Hyo-Jo, Choi, Won-Kyu, Yoo, Subin, Baek, Soojin, Lee, Jaemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225705/
https://www.ncbi.nlm.nih.gov/pubmed/30409131
http://dx.doi.org/10.1186/s12871-018-0625-2

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