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Predictors of disease activity and structural progression after treatment with adalimumab plus methotrexate or continued methotrexate monotherapy in patients with early rheumatoid arthritis and suboptimal response to methotrexate
OBJECTIVES: Methotrexate is considered to be first-line therapy for rheumatoid arthritis (RA). However, a substantial proportion of treated patients do not achieve the desired goals of therapy. This analysis aimed to identify predictors of insufficient response to methotrexate in patients with early...
Autores principales: | Smolen, Josef S, van Vollenhoven, Ronald F, Florentinus, Stefan, Chen, Su, Suboticki, Jessica L, Kavanaugh, Arthur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225797/ https://www.ncbi.nlm.nih.gov/pubmed/30076156 http://dx.doi.org/10.1136/annrheumdis-2018-213502 |
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