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Three-tiered score for Ki-67 and p16(ink4a) improves accuracy and reproducibility of grading CIN lesions

AIMS: To investigate the accuracy and reproducibility of a scoring system for cervical intraepithelial neoplasia (CIN1–3) based on immunohistochemical (IHC) biomarkers Ki-67 and p16(ink4a). METHODS: 115 cervical tissue specimens were reviewed by three expert gynaecopathologists and graded according...

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Detalles Bibliográficos
Autores principales:	van Zummeren, Marjolein, Leeman, Annemiek, Kremer, Wieke W, Bleeker, Maaike C G, Jenkins, David, van de Sandt, Miekel, Heideman, Daniëlle A M, Steenbergen, Renske, Snijders, Peter J F, Quint, Wim G V, Berkhof, Johannes, Meijer, Chris J L M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225805/ https://www.ncbi.nlm.nih.gov/pubmed/30012698 http://dx.doi.org/10.1136/jclinpath-2018-205271

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